| Synonyms | Integrin alpha-2, Collagen receptor, GPIa, CD49b |
|---|---|
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Target | |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Uniprot ID | P17301 |
| Description | Recombinant human ITGA2 Protein with C-terminal 6×His tag |
| Molecular Characterization | ITGA2（Thr30-Thr1132）+6×His tag |
| Expression Host | HEK293 |
| Delivery | In Stock |
| Molecular Weight | The protein has a predicted molecular mass of 121.8 kDa after removal of the signal peptide. The apparent molecular mass of ITGA2-His is approximately 130-250 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Usage | Research use only |
| Background | This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
Human ITGA2 Protein, His Tag
Price: 10μg $80.00 ; 50μg $319.00 ; 100 μg $478.00
Product Data
Images
Figure 1. Human ITGA2, His Tag on SDS-PAGE under reducing condition. |