| Target | |
|---|---|
| Synonyms | Fibroblast growth factor 7;FGF-7;Heparin-binding growth factor 7;HBGF-7;Keratinocyte growth factor;FGF7 |
| Description | Recombinant Human Fibroblast Growth Factor 7/Keratinocyte growth factor is produced by our Mammalian expression system and the target gene encoding Cys32-Thr194 is expressed with a 6His tag at the C-terminus. |
| Delivery | In Stock |
| Uniprot ID | P21781 |
| Expression Host | HEK293 |
| Tag | C-6×His Tag |
| Molecular Characterization | Not available |
| Molecular Weight | 20 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation. |
| Usage | Research use only |
Human KGF (C-6His) Protein
Price: 50 μg $503.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
Figure 2. Measured in a cell proliferation assay using HaCaT cells. The ED50 for this effect is 10.94 ng/ml.