| Target | |
|---|---|
| Synonyms | Fibroblast growth factor 8;Androgen-induced growth factor;Heparin-binding growth factor 8;AIGF;HBGF-8;FGF-8B |
| Description | Recombinant Human/Mouse Fibroblast Growth Factor 8B is produced by our E.coli expression system and the target gene encoding Gln23-Arg215 is expressed. |
| Delivery | In Stock |
| Uniprot ID | P55075-3/P37237-2 |
| Expression Host | E.coli |
| Tag | |
| Molecular Characterization | Not available |
| Molecular Weight | 22.5 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Fibroblast growth factor 8 (FGF-8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen–dependent growth of mouse mammary carcinoma cells. Mouse FGF-8b shares 100% aa identity with human FGF-8b. FGF-8 is widely expressed during embryogenesis, and mediates epithelial–mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. |
| Usage | Research use only |
Human/Mouse FGF-8b Protein
Price: 50 μg $360.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
Figure 2. Measured in a cell proliferation assay using BALB/c 3T3 cells. The ED50 for this effect is 21.87 ng/ml.