| Target | |
|---|---|
| Synonyms | Growth/differentiation factor 8;GDF-8;Myostatin;Mstn;Gdf8 |
| Description | Recombinant Human/Mouse/Rat Growth Differentiation Factor 8 is produced by our Mammalian expression system and the target gene encoding Lys262-Ser375 is expressed. |
| Delivery | In Stock |
| Uniprot ID | O14793 |
| Expression Host | HEK293 |
| Tag | |
| Molecular Characterization | Not available |
| Molecular Weight | 13.1 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues. |
| Usage | Research use only |
Human/Mouse/Rat GDF-8 Protein
Price: 50 μg $891.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.