Tag | C-Flag Tag |
---|---|
Target | |
Synonyms | BB1, BB1R, BRS1, NMB-R |
Description | Human NMBR full length protein-synthetic nanodisc |
Delivery | 6~8weeks |
Uniprot ID | P28336 |
Expression Host | HEK293 |
Protein Families | GPCR,Transmembrane,Druggable Genome, |
Protein Pathways | GPCRDB Class A Rhodopsin-like,Peptide GPCRs,Cancer, |
Molecular Weight | The human full length NMBR protein has a MW of 43.4kDa |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] |
Usage | Research use only |
Human NMBR full length protein-synthetic nanodisc
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
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