| Synonyms | MTC, p140-TrkA, TRK, Trk-A, TRK1, TRKA |
|---|---|
| Molecular Characterization | NTRK1（Ala33-Phe410）+hFc（Glu99-Ala330） |
| Uniprot ID | P04629 |
| Description | Recombinant Human NTRK1 Protein with C-terminal human Fc tag |
| Expression Host | HEK293 |
| Delivery | In Stock |
| Molecular Weight | The protein has a predicted molecular mass of 67.4 kDa after removal of the signal peptide.The apparent molecular mass of NTRK1-hFc is approximately 70-130 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature. |
| Usage | Research use only |
| Background | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008] |
Human NTRK1 Protein, hFc Tag
Price: 10μg $65.00 ; 50μg $259.00 ; 100 μg $389.00
Product Data
Images
Figure 1. Human NTRK1 Protein, hFc Tag on SDS-PAGE under reducing condition.