| Synonyms | CLN1; PPT |
|---|---|
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Target | |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Uniprot ID | P50897 |
| Description | Recombinant human PPT1 protein with C-terminal 6×His tag |
| Molecular Characterization | PPT1（Asp28-Gly306）+6×His tag |
| Expression Host | HEK293 |
| Delivery | In Stock |
| Molecular Weight | The protein has a predicted molecular mass 32.1 of kDa after removal of the signal peptide. The apparent molecular mass of PPT1-His is approximately 33-40 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Usage | Research use only |
| Background | The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008] |
Human PPT1 Protein, His Tag
Price: 10μg $120.00 ; 50μg $450.00 ; 100 μg $660.00
Product Data
Images
Figure 1. Human PPT1 Protein, His Tag on SDS-PAGE under reducing condition.