| Synonyms | AGER |
|---|---|
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Target | |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Uniprot ID | Q15109 |
| Description | Recombinant human RAGE protein with C-terminal 6×His tag |
| Molecular Characterization | RAGE（Thr27-Thr340）+6×His tag |
| Expression Host | HEK293 |
| Delivery | In Stock |
| Molecular Weight | The protein has a predicted molecular mass of 34.2 kDa after removal of the signal peptide. The apparent molecular mass of RAGE-His is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Usage | Research use only |
| Background | The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011] |
Human RAGE Protein, His Tag
Price: 10μg $80.00 ; 50μg $319.00 ; 100 μg $478.00
Product Data
Images
Figure 1. Human RAGE Protein, His Tag on SDS-PAGE under reducing condition.