ARH6; ARHB; MST081; MSTP081; RHOH6
Recombinant Human RHOB Protein with C-terminal human Fc tag
The protein has a predicted molecular mass of 47.4 kDa after removal of the signal peptide. The apparent molecular mass of RHOB-hFc is approximately 35-55 kDa due to glycosylation.
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
10μg $75.00 ; 50μg $274.00 ; 100μg $411.00
Research use only
Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.[UniProtKB/Swiss-Prot Function]
Human RHOB Protein, hFc Tag
Price: 10μg $75.00 ; 50μg $274.00 ; 100μg $411.00
SKU: PME101243 Category: ECD Proteins
Figure 1.Human RHOB Protein, hFc Tag on SDS-PAGE under reducing condition.