| Target | |
|---|---|
| Synonyms | R-spondin-1;hRspo1 |
| Description | Recombinant human RSPO1(21-146) protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q2MKA7 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | RSPO1(Ser21-Ala146) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 39.9 kDa after removal of the signal peptide. The apparent molecular mass of RSPO1(21-146)-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| Usage | Research use only |
Human RSPO1(21-146) Protein, hFc Tag
Price: 10μg $103.00 ; 50μg $388.00 ; 100 μg $568.00
Product Data
Images
Figure 1. Human RSPO1(21-146) Protein, hFc Tag on SDS-PAGE under reducing condition.