Name: Human SCNND full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP100644

Tag	C-Flag Tag
Expression Host	HEK293
Target	SCNND
Synonyms	ENaCd, ENaCdelta, SCNED, dNaCh
Description	Human SCNND full length protein-synthetic nanodisc
Uniprot ID	P51172
Protein Families	Ion Channels: Other
Protein Pathways	N/A
Molecular Weight	The human full length SCNND protein has a MW of 87.9kDa
Delivery	6~8weeks
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution
Sterility	Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use.
Storage&Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated

Human SCNND full length protein-synthetic nanodisc