sp-PME101265 TNFRSF1B Fig.1 SDS PAGE 1

Human TNFRSF1B Protein, His Tag

Price: 10μg $71.00 ; 50μg $259.00 ; 100μg $389.00

SKU: PME101265 Category:
Datasheet
MSDS
Product Data
Target

Synonyms

CD120b;p75;p75TNFR;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80
Description

Recombinant Human TNFRSF1B Protein with C-terminal 6×His tag
Delivery

In Stock
Uniprot ID

P20333
Expression Host

HEK293
Tag

C-6×His Tag
Molecular Characterization

TNFRSF1B(Leu23-Asp257) 6×His tag
Molecular Weight

The protein has a predicted molecular mass of 26.0 kDa after removal of the signal peptide. The apparent molecular mass of TNFRSF1B-His is approximately 35-55 kDa due to glycosylation.
Purity

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
Usage

Research use only
Images

sp-PME101265 TNFRSF1B Fig.1 SDS PAGE 1
Figure 1.Human TNFRSF1B Protein, His Tag on SDS-PAGE under reducing condition.