| Synonyms | CD120b; p75; p75TNFR; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80 |
|---|---|
| Molecular Characterization | TNFRSF1B（Leu23-Asp257）+6×His tag |
| Uniprot ID | P20333 |
| Description | Recombinant Human TNFRSF1B Protein with C-terminal 6×His tag |
| Expression Host | HEK293 |
| Molecular Weight | The protein has a predicted molecular mass of 26.0 kDa after removal of the signal peptide. The apparent molecular mass of TNFRSF1B-His is approximately 35-55 kDa due to glycosylation. |
| Delivery | In Stock |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature. |
| Package | 10μg $71.00 ; 50μg $259.00 ; 100μg $389.00 |
| Usage | Research use only |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008] |
Human TNFRSF1B Protein, His Tag
Price: 10μg $71.00 ; 50μg $259.00 ; 100μg $389.00
Product Data
Images
Figure 1.Human TNFRSF1B Protein, His Tag on SDS-PAGE under reducing condition.