T-cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, Vstm3
Recombinant mouse TIGIT protein with C-terminal human Fc tag
C-Human Fc tag
The protein has a predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of mTIGIT-hFc is approximately 40-55 kDa due to glycosylation.
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
Research use only
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
Mouse TIGIT Protein, hFc Tag
Price: 10μg $100.00 ; 50μg $375.00 ; 100 μg $550.00
SKU: PME-M100053 Category: ECD Proteins
Figure 1. Mouse TIGIT Protein, hFc Tag on SDS-PAGE under reducing condition.