| Target | |
|---|---|
| Synonyms | SARS-CoV-2 BA.5 (Omicron) Spike RBD Protein |
| Description | Recombinant SARS-CoV-2 (Omicron BA.5) S-RBD protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P0DTC2 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | S protein RBD(G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N,N440K, L452R,S477N, T478K, E484A,F486V, Q498R, N501Y, Y505H)(Arg319-Phe541) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 51.4 kDa after removal of the signal peptide. The apparent molecular mass of S-RBD(Omicron BA.5)-hFc is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response. |
| Usage | Research use only |
SARS-CoV-2 (Omicron BA.5) S protein RBD, hFc Tag
Price: 10μg $120.00 ; 50μg $450.00 ; 100 μg $660.00
Product Data
Images
Figure 1. SARS-CoV-2 (Omicron BA.5) S protein RBD, hFc Tag on SDS-PAGE under reducing condition.