CD93 Recombinant Proteins and Flow Antibodies

CD93 is a type I transmembrane glycoprotein containing a C-type lectin-like domain, EGF-like repeats, and a mucin-like extracellular region. It is expressed primarily on vascular endothelial cells and selected myeloid populations and participates in cellular adhesion, phagocytosis, vascular homeostasis, and inflammatory regulation. Increasing evidence has highlighted CD93 as an important regulator of tumor vasculature. Abnormal CD93-associated signaling can influence vessel maturation, permeability, and interactions between tumor vessels and immune cells, making CD93 increasingly relevant to tumor-microenvironment and vascular-targeting research.

DIMA BIOTECH provides human, cynomolgus, and mouse CD93 recombinant ECD proteins in His-, hFc-, and mFc-tagged formats. These proteins support ELISA, antibody screening, affinity studies, protein-interaction assays, and cross-species evaluation. Flow cytometry-validated monoclonal and biosimilar reference antibodies can be used for cell-surface CD93 detection, candidate comparison, and assay development, while PE- and biotin-conjugated formats enable direct flow cytometry and capture-based workflows. Together, these protein, antibody, and tissue tools provide a flexible research platform for studying CD93 biology and evaluating CD93-targeting antibody candidates.