| Tag | C-Flag Tag | 
|---|---|
| Target | |
| Synonyms | RE2 | 
| Description | Human GP161 full length protein-synthetic nanodisc | 
| Delivery | 6~8weeks | 
| Uniprot ID | Q8N6U8 | 
| Expression Host | HEK293 | 
| Protein Families | GPCR,Transmembrane,Druggable Genome, | 
| Protein Pathways | N/A | 
| Molecular Weight | The human full length GP161 protein has a MW of 58.6kDa | 
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. | 
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | 
| Background | The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017] | 
| Usage | Research use only | 
| Conjugate | Unconjugated | 

Human GP161 full length protein-synthetic nanodisc
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