DIMA BIOTECH’s Monoclonal Antibody Discovery Platform represents a next-generation approach to antibody development, built upon its innovative single B cell cloning technology. Unlike traditional single-cell PCR methods that clone antibody genes from one cell at a time, DIMA’s platform first cultures individual B cells in vitro and then clones antibody genes from hundreds of B cells originating from a single parental cell. This unique strategy dramatically improves cloning efficiency and success rate, enabling the discovery of a larger pool of positive lead antibody sequences from immunized animals. By combining this technology with the natural advantages of rabbit monoclonal antibodies—including high affinity, broad epitope recognition, and superior specificity—the platform delivers a comprehensive one-stop solution covering the entire process from antigen design and synthesis to antibody screening, sequencing, and functional validation. With a short development cycle, direct access to full-length antibody genes, and functional protein antigens, DIMA BIOTECH’s platform ensures rapid, high-quality antibody generation for research, diagnostic, and therapeutic applications.
Why Choose Us?
Direct IgG Gene Sequencing: DIMA mAbs enables direct acquisition of IgG gene sequences from immunoreactive B cells, eliminating the need for labor-intensive hybridoma fusion.
Abundance of Immunoreactive B Cell Clones: Our platform isolates over 1000 immunoreactive B cell clones from a single animal, greatly expanding the monoclonal antibody screening potential.
Enhanced Success Rate: DIMA mAbs achieves a much higher success rate than traditional hybridoma platforms, increasing the chances of discovering antibodies with outstanding specificity, sensitivity, and affinity.
Direct Editing and Optimization: With direct access to IgG genes, we can edit, optimize, and humanize antibodies, enabling affinity maturation and efficient cell line construction for diverse applications.
Species Flexibility: DIMA mAbs is independent of myeloma fusion partners, enabling monoclonal antibody development across diverse animal species.
Custom Antibody Request Form
Our Custom Antibody Services
We offer a comprehensive suite of services designed to meet the needs of researchers and biotech companies working with druggable targets. Choose the service that best fits your research goals.
Rabbit mAbs Development
Compared to other animals, rabbits have a unique process of B cell development, and are further removed from rodents and humans in terms of kinship.
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Mouse is the best animal model system to study human diseases. Before clinical trial, mouse disease model is commonly used to simulate the pathogenesis of human diseases and test the drug responses.
View MoreNanobody/VHH mAbs Development
Nanobodies are single-domain antibodies derived from camelids, offering high stability, small size, and strong antigen-binding affinity.
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