Human CXCR4 full length protein-Nanodisc

Price: 20μg $1,214.00; 100μg $2,374.00

SKU: CFP200001 Category: Cell-Free Full-Length Proteins

Tag	N-Strep, C-flag
Target	CXCR4
Synonyms	CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS
Description	Human CXCR4 full length protein-Nanodisc
Delivery	1 week
Uniprot ID	P61073
Expression Host	E.coli
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane
Protein Pathways	Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Leukocyte transendothelial migration
Molecular Weight	The human CXCR4 full length protein has a MW of 42.1kDa
Formulation & Reconstitution	Liquid, 20mM HEPES, 150mM NaCl, pH8.5
Storage&Shipping	Store at -80℃, Ship on dry ice.
Background	A CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome.
Purity	>80%
Usage	Research use only
Conjugate	Unconjugated