CC-CKR-8, CCR-8, CDw198, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, TER1
ELISA, Flow Cyt
ELISA 1/5000-10000;Flow Cyt 1/100
Purified from cell culture supernatant by affinity chromatography
|Formulation & Reconstitution||
Research use only
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
Anti-CCR8 antibody(DM196), Rabbit mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
SKU: DME100196 Category: DimAb monoclonal antibodies
Figure 1. Flow cytometry analysis with Anti-CCR8 (DM196) on Expi293 cells transfected with human CCR8 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).