| Clone ID | 5F5 |
|---|---|
| Target | |
| Synonyms | CDH16;HPT-1;HPT1 |
| Host Species | Rabbit |
| Description | Anti-CDH17 antibody(5F5), IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | Q12864 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | WB; Flow Cyt |
| Recommended Dilutions | WB 1:1000; Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Endotoxin | Less than 1.0 EU/μg by the LAL method. For <1 EU/mg requirements, please contact us for customization. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
| Usage | Research use only |
| Conjugate | Unconjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scr |
Anti-CDH17 antibody(5F5), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data Dima FAQ
Images Dima FAQ
Figure 1.Anti-CDH17 antibody (SKU# DMC100637) at 1/1000 dilution
Lane 1: AGS, whole cell lysate
Lane 2: HT55, whole cell lysate
Secondary : Goat Anti-Rabbit IgG H&L (HRP) at 1/5000 dilution
Predicted band size: 92 kDa
Observed band size: 120 kDa
Figure 2. Flow cytometry analysis of antigen binding of anti-human CDH17 mAb(DMC100637).
(A) DMC100637 does not bind to 293T cells that do not express CDH17
(B) A clear peak shift of DMC100637 was seen compared to the control when incubated with CDH17 -expressing HT55 cells, indicating strong binding of DMC100637 to CDH17.
Antibodies were incubated at 2ug/mL.
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