Target | |
---|---|
Synonyms | CDH16;HPT-1;HPT1 |
Description | Recombinant human CDH17 protein with C-terminal 6×His tag |
Delivery | In Stock |
Uniprot ID | Q12864 |
Expression Host | HEK293 |
Tag | C-6×His Tag |
Molecular Characterization | CDH17(Gln23-Met787) 6×His tag |
Molecular Weight | The protein has a predicted molecular mass of 85.7 kDa after removal of the signal peptide. The apparent molecular mass of CDH17-His is approximately 100-130 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
Usage | Research use only |
Conjugate | Unconjugated |
Human CDH17 Protein, His Tag
Price: 10μg $68.00; 50μg $259.00 ; 100 μg $389.00
Product Data
Images
Figure 1. Human CDH17 Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CDH17 Protein, His Tag (PME100801) can bind Anti-CDH17(ARB102 biosimilar) mAb (BME100198) in a linear range of 0.64–16 ng/mL.
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CDH17 Protein, His Tag (PME100801) can bind Anti-CDH17(TORL-3-600 biosimilar) mAb (BME100233) in a linear range of 3.20–400 ng/mL.
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