Target | |
---|---|
Synonyms | TNFSF18; AITRL; TL6; hGITRL; GITR Ligand |
Host Species | Rabbit |
Description | Anti-GITR Ligand antibody(DM52); Rabbit mAb |
Delivery | In Stock |
Uniprot ID | Q9UNG2 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18:AITR:GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells; and is thought to be important for interaction between T lymphocytes and endothelial cells. |
Usage | Research use only |
Anti-GITR Ligand antibody(DM52); Rabbit mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
Product Data
Images
Figure 1. Expi 293 cell line transfected with irrelevant protein (A) and human GITR-L (B) were surface stained with Rabbit anti-GITR-L monoclonal antibody 15μg/ml (clone: DM52) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
Figure 2. Flow cytometry data of serially titrated Rabbit anti-GITR-L monoclonal antibody (clone: DM52) on H929 cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.