Target | |
---|---|
Synonyms | IBP-7, TAF, IGFBP-rP1, MAC25 protein |
Host Species | Rabbit |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1/100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Buffer | 1XPBS |
Formulation & Reconstitution | Liquid |
Delivery | In Stock |
Usage | Research use only |
Background | This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). |
Anti-IGFBP7 antibody(DMC422), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-IGFBP7 (DMC422) on Expi293 cells transfected with human IGFBP7 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).