| Target | |
|---|---|
| Synonyms | IL-5;TRF;Interleukin-5;EDF |
| Host Species | Rabbit |
| Description | Anti-IL5 antibody(DMC274); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P05113 |
| IgG type | Rabbit:Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation; maturation; recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor; which is a heterodimer; whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2:GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4); interleukin 13 (IL13); and CSF2 . This gene; IL4; and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
| Usage | Research use only |
Anti-IL5 antibody(DMC274); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-IL5 (DMC274) on Expi293 cells transfected with human IL5 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).