Target | |
---|---|
Synonyms | TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L |
Host Species | Rabbit |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | ELISA, Flow Cyt |
Recommended Dilutions | ELISA 1/5000-10000;Flow Cyt 1/100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Buffer | 1XPBS |
Formulation & Reconstitution | Liquid |
Delivery | In Stock |
Usage | Research use only |
Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
Anti-OX40 antibody(DM116), Rabbit mAb
Price: 10μg $99.00 ; 100 μg $438.00 ; 500 μg $1314.00
SKU: DME100116
Category: DimAb monoclonal antibodies
Product Data
Images
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human OX40 protein, hFc-His tagged protein (PME100022) can bind Rabbit anti-OX40 monoclonal antibody (clone: DM116) in a linear range of 6-70 ng/ml.
Figure 2. Flow cytometry analysis with Anti-OX40 (DM116) on Expi293 cells transfected with human OX40 (Blue histogram) or Expi293 transfected with irrelevant protein(Red histogram).