Target | |
---|---|
Synonyms | CD27, TNFRSF7, S152, T14, Tp55 |
Host Species | Rabbit |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | ELISA, Flow Cyt |
Recommended Dilutions | ELISA 1/5000-10000;Flow Cyt 1/100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Buffer | 1XPBS |
Formulation & Reconstitution | Powder |
Delivery | 2-3 weeks |
Usage | Research use only |
Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. |
Biotinylated Anti-CD27 antibody(DM59), Rabbit mAb
Price: 10μg $139.00 ; 100 μg $657.00 ; 500 μg $1971.00