Target | |
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Recommended Dilutions | ELISA 1/5000-10000; Flow Cyt 1/100 |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Description | Biotinylated Anti-GITR antibody(DM78), Rabbit mAb |
Synonyms | AITR, GITR, TNFRSF18, CD357 |
Uniprot ID | Q9Y5U5 |
Applications | ELISA, Flow Cyt |
Host Species | Rabbit |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Purification | Purified from cell culture supernatant by affinity chromatography |
Buffer | 1XPBS |
Formulation & Reconstitution | Powder |
Delivery | 2-3 weeks |
Usage | Research use only |
Background | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Biotinylated Anti-GITR antibody(DM78), Rabbit mAb
Price: 10μg $139.00 ; 100 μg $657.00 ; 500 μg $1971.00