Target | |
---|---|
Synonyms | CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR |
Description | Biotinylated Recombinant human CB1 (1-116) Protein with C-terminal Human Fc Avi tag |
Delivery | In Stock |
Uniprot ID | P21554 |
Expression Host | HEK293 |
Tag | C-Human Fc Avi tag |
Molecular Characterization | CB1(Met1-Gln116) hFc(Glu99-Ala330) Avi tag |
Molecular Weight | The protein has a predicted molecular mass of 41.1 kDa after removal of the signal peptide. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. |
Usage | Research use only |
Conjugate | Biotinylated |
Biotinylated Human CB1 (1-116) Protein, hFc Tag
Price:10μg $79.00; 50μg $301.00 ; 100 μg $452.00
Product Data Dima FAQ
Images Dima FAQ
Figure 1. Biotinylated Human CB1 (1-116) Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Anti-CB1 antibody(DM144), Rabbit mAb (DME100144) can bind Biotinylated Human CB1 (1-116) Protein, hFc Tag (PME100507B) in a linear range of 3.2-16 ng/mL. In order to specifically detect PME100507B, HRP Conjugated Streptavidin was used as detection antibody.
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