| Synonyms | CANN6; CB-R; CNR1; CB1A; CB1K5; CB1R; CNR |
|---|---|
| Uniprot ID | P21554 |
| Expression Host | HEK293 |
| Description | Human CB1 full length protein membrane nanoparticles (MNPs) |
| Molecular Weight | 1416 bp |
| Delivery | 3~4 weeks |
| Formulation & Reconstitution | Supplied in 1xPBS (pH 7.4) |
| Package | 50 μg $1200.00 ; 100 μg $1600.00 |
| Storage & Shipping | The product should be stored at -80°C. Please do not repeated freeze-thaw cycles. |
| Background | The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. |
Human CB1 full length protein-MNP
Price: 50 μg $1200.00 ; 100 μg $1600.00
Product Data
Images
Figure1. Elisa plates were pre-coated with 0.5μg/per well purified human CB1 full length membrane nanoparticles. Serial diluted anti-CB1 monoclonal antibody (DME100144) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CB1 monoclonal antibody binding with CB1 full length membrane nanoparticles is 439.6ng/ml.
Figure2. FACS analysis of CB1 MNPs
A. Negative Control 1: CB1 full length membrane nanoparticles samples were stained only with Goat anti-human lgG 488 secondary antibody.
B. Negative Control 2: Control membrane nanoparticles samples were stained with anti-CB1 antibody (BME100049) at 2μg/mL, followed by Goat anti-human IgG 488 secondary antibody.
C. Negative Control 3: CB1 full length membrane nanoparticles samples were stained with anti-CCR8 antibody (an irrelevant antibody) at 2μg/mL, followed by Goat anti-human IgG 488 secondary antibody.
D. CB1 full length membrane nanoparticles samples were stained with anti-CB1 antibody (BME100049) at 2μg/mL, followed by Goat anti-human IgG 488 secondary antibody.