T3E; TCRE; IMD18; CD3epsilon
Recombinant Cynomolgus CD3E protein with C-terminal human Fc tag
C-Human Fc tag
The protein has a predicted molecular mass of 37.0 kDa after removal of the signal peptide. The apparent molecular mass of cCD3E-hFc is approximately 35-55 kDa due to glycosylation.
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Research use only
Cynomolgus CD3E Protein, hFc Tag
Price: 10μg $258.00 ; 50μg $969.00 ; 100μg $1421.00
SKU: PME-C100037 Category: ECD Proteins
Figure 1. Cynomolgus CD3E Protein, hFc Tag on SDS-PAGE under reducing condition.