Synonyms | CANN6; CB-R; CNR1; CB1A; CB1K5; CB1R; CNR |
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Uniprot ID | P21554 |
Expression Host | HEK293 |
Description | Human CB1 full length protein-synthetic nanodisc |
Molecular Weight | 1416 bp |
Delivery | 3~4 weeks |
Formulation & Reconstitution | Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0) |
Package | 50 μg $4400.00 ; 100 μg $8000.00 |
Storage & Shipping | The product should be stored at -80°C. Please do not repeated freeze-thaw cycles. |
Background | The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. |
Human CB1 full length protein-synthetic nanodisc
Price: 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Figure1. Elisa plates were pre-coated with Flag Tag CB1-Nanodisc (0.2μg/per well). Serial diluted anti-CB1 monoclonal antibody (DME100144) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CB1 monoclonal antibody binding with CB1-Nanodisc is 41.62ng/ml.
Figure2. Human CB1-Nanodisc, Flag Tag on SDS-PAGE