| Delivery | In Stock |
|---|---|
| Package | 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00 |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Molecular Weight | The human full length CB2 protein has a MW of 39.7 kDa |
| Target | |
| Formulation & Reconstitution | |
| Uniprot ID | P34972 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Synonyms | CB-2; CNR2; CX5 |
| Expression Host | HEK293 |
| Description | Human CB2 full length protein-synthetic nanodisc |
| Background | The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. |
Human CB2 full length protein-synthetic nanodisc
Price: 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Figure1. Elisa plates were pre-coated with Flag Tag CB2-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody (Origene, TA592569) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CB2-Nanodisc is 1.557ng/ml.
Figure2. Human CB2-Nanodisc, Flag Tag on SDS-PAGE