| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | LAMP-3; ME491; MLA1; OMA81H; TSPAN30 |
| Description | Human CD63 full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | P08962 |
| Expression Host | HEK293 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Lysosome |
| Molecular Weight | The human full length CD63 protein has a MW of 25.6 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human CD63 full length protein-synthetic nanodisc
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Product Data Dima FAQ
Images Dima FAQ
Figure 1. Elisa plates were pre-coated with Flag Tag CD63-Nanodisc (0.2μg/per well). Serial diluted anti-CD63 monoclonal antibody (DMC100425) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CD63 monoclonal antibody binding with CD63-Nanodisc is 94.22ng/ml.
Figure 2. Human CD63-Nanodisc, Flag Tag on SDS-PAGE
Figure 3. ELISA assay evaluating the stability of Human CD63 full-length protein in synthetic nanodiscs (SKU# FLP100030).
Figure 4. ELISA assay evaluating the stability of Human CD63 full-length protein in synthetic nanodiscs (SKU# FLP100030).
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