Synonyms | CD63 antigen,Granulophysin,LAMP-3,Limp1,Melanoma-associated antigen ME491,OMA81H,Ocular melanoma-associated antigen,Tetraspanin-30, Tspan-30 |
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Target | |
Uniprot ID | P08962 |
Description | Recombinant human CD63 protein with C-terminal human Fc tag |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Molecular Characterization | CD63(Ala103-Val203)+hFc(Glu99-Ala330) |
Expression Host | HEK293 |
Delivery | In Stock |
Molecular Weight | The protein has a predicted molecular mass of 37.7 kDa after removal of the signal peptide. The apparent molecular mass of CD63-His is approximately 35-55 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
Usage | Research use only |
Background | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012] |
Human CD63 Protein, hFc Tag
Price: 10μg $65.00 ; 50μg $259.00 ; 100 μg $389.00
Product Data
Images
Figure 1. Human CD63 Protein, hFc Tag on SDS-PAGE under reducing condition.