Target | |
---|---|
Synonyms | HPT-1; HPT1 |
Description | Recombinant human CDH17(450-566) Protein with C-terminal human Fc tag |
Delivery | In Stock |
Uniprot ID | Q12864 |
Expression Host | HEK293 |
Tag | C-Human Fc tag |
Molecular Characterization | CDH17(Glu450-Phe566) hFc(Glu99-Ala330) |
Molecular Weight | The protein has a predicted molecular mass of 38.8 kDa after removal of the signal peptide. The apparent molecular mass of CDH17(450-566)-hFc is approximately 35-70 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
Usage | Research use only |
Conjugate | Unconjugated |
Human CDH17(450-566) Protein, hFc Tag
Price:10μg $95.00 ; 50μg $330.00 ; 100μg $500.00
Product Data
Images
Figure 1. Human CDH17(450-566) Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CDH17(450-566) Protein, hFc Tag (PME101566) can bind Anti-CDH17 antibody, IgG1 Chimeric mAb in a linear range of 3.20–80 ng/mL.
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