| Synonyms | Claudin 6, Claudin-6, Skullin,Claudin6 |
|---|---|
| Uniprot ID | P56747 |
| Expression Host | HEK293 |
| Description | Human CLDN6 full length protein-synthetic nanodisc |
| Molecular Weight | 660bp |
| Delivery | 3~4 weeks |
| Formulation & Reconstitution | Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0) |
| Package | 50 μg $4400.00 ; 100 μg $8000.00 |
| Storage & Shipping | The product should be stored at -80°C. Please do not repeated freeze-thaw cycles. |
| Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. |
Human CLDN6 full length protein-synthetic nanodisc
Price: 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Figure1. Elisa plates were added with Flag Tag CLDN6-Nanodisc (0.5μg/per well) on an anti-Flag monoclonal antibody pre-coated (0.5μg/per well) plate. Serial diluted anti-CLDN6 monoclonal antibody (BME100082) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CLDN6 monoclonal antibody binding with CLDN6-Nanodisc is 66.99ng/ml.
Figure2. Human CLDN6-Nanodisc, Flag Tag on SDS-PAGE