| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | D2DR; D2R |
| Description | Human DRD2 full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | P14416 |
| Expression Host | HEK293 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Gap junction, Neuroactive ligand-receptor interaction |
| Molecular Weight | The human full length DRD2 protein has a MW of 50.6 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human DRD2 full length protein-synthetic nanodisc
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Product Data Dima FAQ
Images Dima FAQ
Figure1. Elisa plates were pre-coated with Flag Tag DRD2-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with DRD2-Nanodisc is 3.314ng/ml.
Figure2. WB analysis of Human DRD2-Nanodisc with anti-Flag monoclonal antibody at 1/5000 dilution, followed by Goat Anti-Rabbit IgG HRP at 1/5000 dilution
Related Products
Full Length Transmembrane Proteins
SKU: FLP120230 Target: DRD2
Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00
ECD Proteins
SKU: PME101721 Target: DRD2
Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00