| Target | |
|---|---|
| Synonyms | ELAPOR1,Endosome-Lysosome Associated Apoptosis And Autophagy Regulator 1,EIG121,KIAA1324 |
| Description | Recombinant Human Endosome/Lysosome-associated Apoptosis and Autophagy Regulator 1 is produced by our Mammalian expression system and the target gene encoding Thr42-Lys910 is expressed with a 6His tag at the C-terminus. |
| Delivery | In Stock |
| Uniprot ID | Q6UXG2 |
| Expression Host | HEK293 |
| Tag | C-6His tag |
| Molecular Characterization | #N/A |
| Molecular Weight | 96.2 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Storage & Shipping | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Usage | Research use only |
| Background | Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated with breast and endometrial cancers,but its mechanism of action remains unknown.May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. That EIG121 is a good endometrial biomarker associated with a hyperestrogenic state and estrogen-related type I endometrial adenocarcinoma. |
Human ELAPOR1 (C-6His) Protein
Price: 50 μg $243.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.