| Delivery | In Stock |
|---|---|
| Package | 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00 |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Molecular Weight | The human full length FZD4 protein has a MW of 60.3 kDa |
| Target | |
| Formulation & Reconstitution | |
| Uniprot ID | Q9ULV1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
| Synonyms | CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4 |
| Expression Host | HEK293 |
| Description | Human FZD4 full length protein-synthetic nanodisc |
| Background | A member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. |
Human FZD4 full length protein-synthetic nanodisc
Price: 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Figure1. Elisa plates were pre-coated with Flag Tag FZD4-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody (Origene, TA592569) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with FZD4-Nanodisc is 1.843ng/ml.
Figure2. Human FZD4-Nanodisc, Flag Tag on SDS-PAGE