Package | 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00 |
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Molecular Weight | The human full length FZD7 protein has a MW of 63.4 kDa |
Delivery | 3-4 weeks |
Formulation & Reconstitution | Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0) |
Target | |
Storage & Shipping | The product should be stored at -80°C. Please do not repeated freeze-thaw cycles. |
Uniprot ID | O75084 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
Synonyms | FzE3 |
Expression Host | HEK293 |
Description | Human FZD7 full length protein-synthetic nanodisc |
Background | Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008] |

Human FZD7 full length protein-synthetic nanodisc
Price: 10ug$900.00;50 μg $4400.00 ; 100 μg $8000.00