| Target | |
|---|---|
| Synonyms | Insulin-Like Growth Factor I;IGF-I;Mechano Growth Factor;MGF;Somatomedin-C;IGF1;IBP1 |
| Description | Recombinant Human Insulin-like Growth Factor I(4-70) is produced by our E.coli expression system and the target gene encoding Thr52-Ala118 is expressed. |
| Delivery | In Stock |
| Uniprot ID | P05019 |
| Expression Host | E.coli |
| Tag | |
| Molecular Characterization | Not available |
| Molecular Weight | 7.3 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone. |
| Usage | Research use only |
Human IGF-I (67AA) Protein
Price: 50 μg $100.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.