| Target | |
|---|---|
| Synonyms | Insulin-like growth factor-binding protein 1; IBP-1; IGF-binding protein 1; IGFBP-1; Placental protein 12; PP12 |
| Package | 10 μg $67.00 ; 50 μg $202.00 |
| Description | Recombinant Human Insulin-like Growth Factor-binding Protein 1 is produced by our Mammalian expression system and the target gene encoding Ala26-Asn259 is expressed with a 6His tag at the C-terminus. |
| Delivery | In Stock |
| Uniprot ID | P08833 |
| Expression Host | HEK293 |
| Tag | C-6His tag |
| Molecular Characterization | #N/A |
| Molecular Weight | 26.1 KDa |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation & Reconstitution | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Storage & Shipping | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Usage | Research use only |
| Background | Insulin-like growth factor-binding protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature protein. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). |
Human IGFBP-1 (C-6His) Protein
Price: 10 μg $67.00 ; 50 μg $202.00
Product Data
Images
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.