| Synonyms | ANKTM1; FEPS; FEPS1 |
|---|---|
| Uniprot ID | O75762 |
| Expression Host | HEK293 |
| Description | Human TRPA1 full length protein-synthetic nanodisc |
| Molecular Weight | 3357 bp |
| Delivery | 3~4 weeks |
| Formulation & Reconstitution | Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0) |
| Package | 50 μg $4400.00 ; 100 μg $8000.00 |
| Storage & Shipping | The product should be stored at -80°C. Please do not repeated freeze-thaw cycles. |
| Background | The structure of the protein is highly related to both the protein ankyrin and transmembrane proteins. This protein is activated by a large variety of structurally unrelated electrophilic and non-electrophilic chemical compounds. Electrophilic ligands activate TRPA1 by interacting with critical N-terminal Cys residues in a covalent manner, whereas mechanisms of non-electrophilic ligands are not well determined. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system. |
Human TRPA1 full length protein-synthetic nanodisc
Price: 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Figure1. Elisa plates were pre-coated with Flag Tag TRPA1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody (Origene, TA592569) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with TRPA1-Nanodisc is 7.433ng/ml.
Figure2. Human TRPA1-Nanodisc, Flag Tag on SDS-PAGE