CEACAM5/CEA Recombinant Proteins, Antibodies and Research Tools

Human carcinoembryonic antigen-related cell adhesion molecule 5 (CEA cell adhesion molecule 5, CEACAM5), also known as CEA and CD66e, is a cell-surface glycoprotein and a well-established member of the carcinoembryonic antigen-related cell adhesion molecule family. In addition to its long-standing use as a tumor-associated biomarker, CEACAM5 is frequently expressed in epithelial malignancies and has become an important target for ADC, multispecific antibody, and cell therapy research. More about the progress of targeted CEACAM5 tumor therapy research >>

DIMA BIOTECH provides CEACAM5 ECD proteins from multiple species, recombinant proteins covering different extracellular domains, rabbit monoclonal antibodies, biosimilar reference antibodies, PE- and biotin-conjugated antibodies, and DiSliceX™ tumor tissue slides. The extensive panel of extracellular-domain proteins is particularly useful for antibody screening, ELISA, epitope mapping, and binding characterization. Flow cytometry-validated antibodies support cell-surface CEACAM5 detection, candidate comparison, and assay development, while PE-conjugated antibodies enable direct flow cytometry and DiSliceX™ slides support IHC optimization and tissue-expression studies.

Beyond off-the-shelf research reagents, DIMA BIOTECH supports further development and functional evaluation of CEACAM5-targeting molecules and has established CEACAM5 CAR constructs with in vitro functional validation capabilities, enabling integrated antibody screening, engineering, and cell-based evaluation workflows.