| Common Name | CDP-771, CMA-676, WAY-CMA-676, |
|---|---|
| Synonyms | CD33;SIGLEC3;gp67 |
| Conjugate | Unconjugated |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Host Species | Humanized |
| IgG type | Human IgG4 – Kappa |
| Reactivity | Human |
| Target | |
| Uniprot ID | P20138 |
| Description | Anti-CD33 (gemtuzumab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only |
Anti-CD33 (gemtuzumab biosimilar) mAb
Price: 50μg $82.00 ; 100 μg $162.00
Product Data Dima FAQ
Images Dima FAQ
Figure 1. HEK293 cell line transfected with irrelevant protein (B) and human CD33 (A) were surface stained with anti-CD33 neutralizing antibody 1μg/ml (gemtuzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.
Figure 2. Flow cytometry analysis of antigen binding of anti-human CD33 mAb(BME100015).
(A) A clear peak shift of BME100015 was seen compared to the control when incubated with CD33-expressing 8226 cells, indicating strong binding of BME100015 to CD33. Antibodies were incubated at 2 μg/mL.
Figure 3. Flow cytometry analysis of antigen binding of anti-human CD33 mAb(BME100015).
(A) BME100015 does not bind to 293T cells that do not express CD33.
(B) A clear peak shift of BME100015 was seen compared to the control when incubated with CD33 -expressing THP-1 cells, indicating strong binding of BME100015 to CD33 . Antibodies were incubated at 5 μg/mL.
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