| Tag | C-Flag&Avi Tag |
|---|---|
| Expression Host | HEK293 |
| Target | |
| Synonyms | 5-HT2A, HTR2 |
| Description | Biotinylated Human 5HT2A full length protein-synthetic nanodisc |
| Uniprot ID | P28223 |
| Protein Families | GPCR,Transmembrane,Druggable Genome, |
| Protein Pathways | GPCRDB Class A Rhodopsin-like,GPCRDB Other,Monoamine GPCRs,Metabolic and Obesity, |
| Molecular Weight | The human full length 5HT2A protein has a MW of 52.6kDa |
| Delivery | 6~8weeks |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Sterility | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| Usage | Research use only |
| Conjugate | Biotinylated |
Biotinylated Human 5HT2A full length protein-synthetic nanodisc
Price: 10 μg $990.00 ; 50 μg $4840.00 ; 100 μg $8800.00
Product Data Dima FAQ
Images Dima FAQ
Related Products
Full Length Transmembrane Proteins
SKU: FLP100030 Target: CD63 Tag: C-Flag Tag
Expression Host: HEK293
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Full Length Transmembrane Proteins
SKU: FLP100031 Target: GPR75 Tag: C-Flag Tag
Expression Host: HEK293
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Full Length Transmembrane Proteins
SKU: FLP100024 Target: CCR4 Tag: C-Flag Tag
Expression Host: HEK293
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Full Length Transmembrane Proteins
SKU: FLP100026 Target: CD20 Tag: C-Flag Tag
Expression Host: HEK293
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100022 Target: TM4SF1 Tag: C-Flag Tag
Expression Host: HEK293
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Full Length Transmembrane Proteins
SKU: FLP100016 Target: CCR4 Tag: C-Flag Tag
Expression Host: HEK293
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100019 Target: ADORA2A Tag: C-Flag Tag
Expression Host: HEK293
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100021 Target: TM4SF1 Tag: C-Flag Tag
Expression Host: HEK293
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100001 Target: CCR8 Tag: C-Flag Tag
Expression Host: HEK293
Price: 50 μg $1200.00 ; 100 μg $1600.00