| Synonyms | CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R |
|---|---|
| Uniprot ID | P41597 |
| Expression Host | HEK293 |
| Description | Human CCR2 full length protein-synthetic nanodisc |
| Molecular Weight | 1122 bp |
| Delivery | 3~4 weeks |
| Formulation & Reconstitution | Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0) |
| Package | 50 μg $4400.00 ; 100 μg $8000.00 |
| Storage & Shipping | The product should be stored at -80°C. Please do not repeated freeze-thaw cycles. |
| Background | The protein is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. |
Human CCR2 full length protein-synthetic nanodisc
Price: 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Figure1. Elisa plates were pre-coated with Flag Tag CCR2-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody (Origene, TA592569) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CCR2-Nanodisc is 7.62ng/ml.
Figure2. Human CCR2-Nanodisc, Flag Tag on SDS-PAGE
Figure3. WB analysis of Human CCR2-Nanodisc with anti-CCR2 monoclonal antibody (BME100087), followed by Goat Anti-Human IgG HRP at 1/5000 dilution