| Target | |
|---|---|
| Synonyms | BN-1;C-C CKR-6;CC-CKR-6;CCR-6;CD196;CKR-L3;CKRL3;CMKBR6;DCR2;DRY6;GPR29;GPRCY4;STRL22 |
| Description | Recombinant Human CCR6 with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P51684 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | CCR6(Met1-Leu47) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 31.6 kDa after removal of the signal peptide. The apparent molecular mass of CCR6-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
Human CCR6 Protein, hFc Tag
Price: 10μg $69.00 ; 50μg $274.00 ; 100 μg $411.00
Product Data
Images
Figure 1. Human CCR6 Protein, hFc Tag on SDS-PAGE under reducing condition.