Synonyms | CC-CKR-6, CKR-L3, DRY6, GPRCY4, CD196 |
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Tag | C-Mouse Fc tag |
Target | |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
Uniprot ID | P51684 |
Description | Recombinant human CCR6 protein with C-terminal mouse Fc tag |
Delivery | In Stock |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Package | 10μg $103.00 ; 50μg $388.00 ; 100 μg $568.00 |
Molecular Characterization | CCR6(Met1-Leu47)+mFc(Pro99-Lys330) |
Expression Host | HEK293 |
Molecular Weight | The protein has a predicted molecular mass of 31.7 kDa after removal of the signal peptide. The apparent molecular mass of CCR6-mFc is approximately 35-55 kDa due to glycosylation. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Usage | Research use only |
Background | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
Human CCR6 Protein, mFc Tag
Price: 10μg $103.00 ; 50μg $388.00 ; 100 μg $568.00
Product Data
Images
Figure 1. Human CCR6 Protein, mFc Tag on SDS-PAGE under reducing condition.