Name: Human GP135-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120262

Tag	C-Flag&Strep Tag
Target	GP135
Synonyms	HUMNPIIY20
Description	Human GP135-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q8IZ08
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Other,
Molecular Weight	The human full length GP135-Strep protein has a MW of 51.7 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538).[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated

Human GP135-Strep full length protein-synthetic nanodisc